Scientists have emphasised the small study did not point towards a cure for the cognitive disorders of people with Down Syndrome and that far more research is needed.
WHO chief Tedros Adhanom Ghebreyesus says the Americas account for more than half of reported cases as several countries in the continent continue to see increasing numbers of infections.
So far, more than 41,000 cases of monkeypox and 12 deaths have been reported from 96 countries, with the majority of cases from the United States.
The new case of a 46-year-old woman, who died on August 15, comes weeks after the country declared its 14th outbreak over.
Vaccine alliance Gavi has highlighted the improvement since the start of the year, when on average only 31 percent of people across the 92 lower-income countries had received the two initial jabs.
Disease leaves at least 157 children dead with more than 2,000 infections recorded across the landlocked African country, officials say.
The UN health agency says monkeypox was given its name before current best practices in naming diseases.
The announcement came following reports of monkeypox-related fatalities outside Africa, seen in Spain and Brazil this week.
Studies led by University of Glasgow and Great Ormond Street Hospital in London have suggested that another common virus, adeno-associated virus 2 (AAV2), was present in most cases.
Imvanex has been approved in the EU since 2013 for the prevention of smallpox and considered a potential vaccine for monkeypox because of the similarity between the monkeypox virus and the smallpox virus.
Nations approved, through consensus, that "they will work to conclude a new, legally-binding international pandemic agreement," says World Health Organization.
World Health Organization forecasts a challenging autumn and winter for Europe as the 53 countries in European region reported nearly 3 million new coronavirus infections last week.
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