The two sides will discuss counterterrorism operations against the Daesh and Al Qaeda, humanitarian assistance, Afghanistan's devastated economy, and safe passage for US and Afghan aids out of Kabul.
By decreasing sectarian tensions, a changing Taliban and post-revolution Iran, the two anti-American neighbours, have shown signs of goodwill to each other in recent years.
The agreement’s language suggests that the US was prepared to accept the Taliban’s eventual takeover of Afghanistan.
Questions surround Khalilzad, an enigmatic diplomat who presided over US failures in Iraq and now the return of the Taliban to power in Afghanistan.
The current regional balance of power, in which Russia and China see the Taliban as the lesser of two evils, and a hasty US withdrawal helped the group march across Afghanistan, experts say.
NATO chief Jens Stoltenberg describes security situation as "deeply challenging" with most foreign troops already out of the country where insurgents are pushing forward with their sweeping assault.
As a Taliban offensive spreads across Afghanistan, Ashraf Ghani will be hoping for a significant commitment of aid post troop withdrawal with Joe Biden expected to pressure the Afghan leader to strike a deal with the insurgents.
Ahmad Massoud envisions a political setup in which people of every ethnicity have a say.
The Taliban denies any involvement in targeting Saleh, but experts think the latest attack was aimed at 'poisoning' the upcoming intra-Afghan talks.
Top US negotiator, Zalmay Khalilzad is known to have connections with shadowy figures in Afghanistan and experts are struggling to understand what exactly he has agreed with the Taliban.
Islamabad plays a crucial role in advancing mediation efforts between the Taliban and Washington, positioning itself as a powerful bargaining force in the future of Afghanistan.
The negotiations appear to give the Taliban some degree of political legitimacy in Afghanistan following the complete withdrawal of US forces and in exchange the insurgent group is expected to stop harbouring 'terrorists'.
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