The four-member team was assigned to conduct more than 200 experiments and technology demonstrations aboard the space station.
An uncrewed Russian Soyuz vessel took off from Kazakhstan for the ISS to eventually bring home US astronaut Frank Rubio and Russian cosmonauts Dmitry Petelin and Sergei Prokopyev whose return vehicle was damaged by a tiny meteoroid.
Russia's Sergey Ryzhikov and Sergey Kud-Sverchkov along with NASA's Kate Rubins landed on barren land at 0455 GMT in Kazakhstan.
The craft launched a repeat of the docking manoeuvres after the failure of the first attempt, which had been scheduled for 0530 GMT, the agencies said.
A Russian-made Soyuz rocket blasted a three-man crew into orbit on Monday, beginning the first manned voyage to the International Space Station since a mission in October was aborted in midair because of a rocket malfunction.
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