Venezuela's top prosecutor says she has "a lot" of proof implicating the president in a corruption scheme, and warns that her life remains in danger.
Earlier this month US President Donald Trump slammed Nicolas Maduro, saying the US had many options for Venezuela including a possible military operation if necessary.
Ex-chief prosecutor Luisa Ortega, who fled Venezuela after being hit with charges of alleged corruption, was offered asylum by Colombia as it joined other countries in criticising President Nicolas Maduro's rule.
Colombian migration authorities confirmed that Luisa Ortega Diaz and her husband German Ferrer landed in Bogota aboard a private plane from Aruba.
The opposition, which controls the legislature, has been sidelined and its leaders are under threat of arrest after organising protests.
President Nicolas Maduro's attempt to end Venezuela's constitutional crisis starts work on Friday. But the opposition and countries critical of Maduro dispute the new body's legitimacy.
The sanctions freeze any assets Maduro may have in US jurisdictions and bar Americans from doing business with him. Maduro says the sanctions reflect Trump's "desperation" and "hatred" for Venezuela's socialist government.
The defiant chief prosecutor, Luisa Ortega, has emerged as Venezuelan President Nicolas Maduro's most-feared critic.
Venezuela's President Maduro warns that he and supporters would take up arms if his socialist government was violently overthrown by "Washington-backed opponents" who have been on the streets since April.
Luisa Ortega says her family is being harassed and followed by intelligence agents since she challenged President Nicolas Maduro.
Venezuela's attorney general, Luisa Ortega, says Maduro's plan to create a new congress threatens to "eliminate" democracy.
Clash between riot police and angry protesters marks the latest violence in nearly two months of unrest in which 58 people have died.
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