Mohamed Salah scores hat-trick in 5-0 win at Old Trafford registering Liverpool's largest success against United since 1925. Separately, Real Madrid beat Barcelona 2-1 at the first football match since Ramos and Messi's departure.
Ahead of the match, Chelsea and Tottenham paid an emotional tribute to their former striker Jimmy Greaves who died aged 81.
UEFA announces nominees for the 2020-21 club competition awards, featuring Borussia Dortmund's Erling Haaland, Paris St Germain's Kylian Mbappe and Bayern Munich's Robert Lewandowski for the best men's forward category.
Lukaku becomes the second most expensive player in Premier League history after his return to Chelsea from Inter Milan.
The Spaniard, who has lost his place as number one since joining the club in 2018, was introduced late in extra-time as a substitute for the shootout by coach Thomas Tuchel.
Chelsea's Kai Havertz goal secured a tense 1-0 victory over Manchester City in Porto, shattering Pep Guardiola's dream of lifting the trophy for the third time, a decade on from his last triumph.
Residents in Portugal's Porto are afraid of a massive spike in infections because of the highly contagious British variant as English football fans enjoy the city without wearing masks.
The Blues ousted Los Blancos 3-1 on aggregate after a 2-0 victory in the second leg of their semifinal.
A 1-0 win at West Ham, coupled with Liverpool conceding a stoppage-time goal to draw with lowly Newcastle 1-1 at Anfield, saw Chelsea open up a gap to its two main rivals for a top-four finish in the English Premier League.
Arsenal, Chelsea, Liverpool, Manchester United, Manchester City and Tottenham desert plans to join breakaway Super League, imploding the breakaway project after backlash from their supporters and warnings from government.
Jose Mourinho has been sacked by Tottenham just six days before they play Manchester City in the League Cup final, the club announced on Monday.
European football's governing body UEFA says players from the 12 major clubs could face international exile while calling splinter league "a cynical project... founded on the self-interest of a few clubs".
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