The move reflects Serb opposition to the Bosnian law amendments imposed last week by Valentin Inzko, the outgoing High Representative in Bosnia. The amendments aimed to outlaw attempts at minimizing the scope of the 1995 massacre in Srebrenica.
Local Bosnian authorities are pleading for more resources to help the health system as the country battles a surge in infections with no vaccination drive in sight.
The closure puts thousands of jobs at the factory, its contractors and suppliers at risk.
About 3.35 million registered voters will elect five presidents and 14 prime ministers in the nation's complex political system. Leading Serb, Croat and Muslim Bosniak parties campaigned on nationalist ticket in the run up to the vote.
Milorad Dodik says he will prioritise the interests of Bosnia's Serb-dominated region as he becomes a candidate to become president of a state he has repeatedly attacked as unviable and harmful for Serbs.
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