Security officers fired barrages of tear gas canisters on protesters demanding a restoration of the transition to civilian rule, witnesses say.
Waving flags, beating drums, dancing and chanting, large crowds marched in several cities as security forces blocked bridges, cut phone lines and restricted the internet.
The opposition said dozens more have been injured during the demonstration – the latest in nearly four months of anti-government protests.
Though the countrywide demonstrations entered its sixth day on Monday, the army pledged to stand by President Omar Bashir.
An umbrella coalition of professional unions says doctors in the African country would strike to "paralyse" government but continue to deal with emergencies.
The River Nile State declared emergency and curfew on Wednesday as protesters called for overthrow of Omar al Bashir's government
The protests follow a state of emergency that was declared in the city of Atbara after hundreds of people protested against price increases and set fire to the local headquarters of the ruling party.
Hundreds of people torched the ruling party's headquarters in Atbara city to protest against the rise in bread prices.
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