In their bid to pressure Maduro into abandoning a weekend election for a super-congress, millions of Venezuelans are expected to take part in a nationwide strike from Wednesday.
Venezuela's Supreme Court says Lopez had been granted house arrest due to health problems, but his family members were unable to identify what those were. Government supporters often note Lopez's role in a short-lived 2002 coup against Hugo Chavez.
Venezuela's President Maduro warns that he and supporters would take up arms if his socialist government was violently overthrown by "Washington-backed opponents" who have been on the streets since April.
Opposition legislators have taken their message onto public transport. On the streets, two more students died in the latest anti-Maduro demonstrations. The death toll since the start of the protests in April is now more than 70.
Demonstrators in the city of Barinas set fire to late president Hugo Chavez's childhood home and destroyed at least five statues commemorating Chavez.
The Vatican has offered to mediate as the political crisis in Venezuela shows no sign of ending.
The opposition says it will not allow President Nicolas Maduro to change Venezuela's constitution "by act of force."
Crowds of students clashed with riot police in the latest in a wave of unrest as the opposition vowed no respite in its drive to oust President Nicolas Maduro.
Venezuela's Justice Ministry said on Friday 12 people were killed in violent incidents in Caracas overnight during violent anti-government protests.
President Maduro seeks to rally support from allies amidst growing domestic and international pressures to step down.
Protests began after Venezuelan authorities blocked opposition to hold a rally in the country's capital Caracas.
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