Wuhan, site of the world's first Covid-19 outbreak in late 2019, reported around 20 to 25 new infections a day this week, prompting orders for more than 800,000 people in one district to stay at home until Sunday.
Chinese cities from Wuhan in central China to Xining in the northwest are doubling down on Covid-19 curbs, sealing up buildings and locking down districts in a scramble to halt widening outbreaks.
China on Thursday reported a third straight day of more than 1,000 new Covid cases nationwide, a modest tally compared with the tens of thousands per day that sent Shanghai into a full-blown lockdown earlier this year but enough to trigger more curbs and restrictions across the country.
China's coronavirus caseload has remained small by global standards, but its ultra-strict and disruptive containment measures this year against the highly transmissible Omicron variant have weighed heavily on the world's second-largest economy.
Guangzhou, China's fourth-biggest city by economic output and the provincial capital of Guangdong, on Thursday sealed up more streets and neighbourhoods and kept people in their homes as new areas were deemed high-risk in a Covid resurgence that persisted into its fourth week.
"Many of my friends and coworkers have been under lockdown at home," said Guangzhou resident Lily Li, 28.
"The situation is still unstable. Many places are under lockdown. Classes have stopped and entertainment venues have been suspended too. The gym that I often go to has also been closed."
As of October 24, 28 cities were implementing varying degrees of lockdown measures, with around 207.7 million people affected in regions that comprise around 25.6 trillion yuan ($3.55 trillion) of China's gross domestic product, according to Nomura.
That's the equivalent of nearly a quarter of China's 2021 GDP.
Mainland China shares edged lower on Thursday as the outbreaks dragged on sentiment, while gloomy data on a Covid-battered industrial sector cast a further pall over markets.
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Wuhan, site of the world's first Covid-19 outbreak in late 2019, reported around 20 to 25 new infections a day this week, prompting local authorities to order more than 800,000 people in one district to stay at home until Sunday.
"I don't know what to do. If we can still survive living like this then I suppose that's what we'll do," said a Wuhan resident surnamed Chang, 38.
In Xining, capital of Qinghai province, social media posts told of food shortages and price inflation for essential goods as health authorities in the city of 2.5 million people raced to contain a Covid rebound following the week-long National Day holiday in early October.
"To reduce the risk of transmission, some vegetable and fruit stores have been closed and put under quarantine," said a Xining government official on Wednesday.
Other large cities across China including Zhengzhou, Datong and Xian have implemented new curbs this week to rein in local outbreaks.
In Beijing, the Universal Resort theme park was shut on Wednesday after at least one visitor tested positive for the coronavirus.
China has repeatedly vowed to stick to its zero-tolerance response to Covid-19 and implement what the authorities say are necessary measures to contain the virus.